Modality
Stapled/constrained peptide
Hydrocarbon or lactam stapling to lock helical or bioactive conformations, improving cell permeability and target engagement.
Examples
- AMG 133 / maritide
Related assets
View all →| Asset | Stage | Mechanism |
|---|---|---|
| Maritide | Phase 1/2 | Anti-GIPR monoclonal antibody conjugated to two GLP-1 agonist peptides, designed for monthly dosing. |